Epigenetic chromatin modification by amber suppression technology

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Epigenetic Modification of Plant Chromatin

Based on the analysis of 20 different monocot and eudicot species, we propose that the centromeric distribution of the phosphorylated histone H2AThr120 is evolutionary highly conserved across species with monoand holocentric chromosomes. Therefore, antibodies recognizing the phosphorylated threonine 120 of the histone H2A can serve as a universal marker for the cytological detection of centrome...

متن کامل

Epigenetic Battles Underfoot: Allelopathy among Plants Can Target Chromatin Modification.

Laura A. Lewis, Krzysztof Polanski, Marta de Torres-Zabala, Siddharth Jayaraman, Laura Bowden, Jonathan Moore, Christopher A. Penfold, Dafyd J. Jenkins, Claire Hill, Laura Baxter, Satish Kulasekaran, William Truman, George Littlejohn, Justyna Prusinska, Andrew Mead, Jens Steinbrenner, Richard Hickman, David Rand, David L. Wild, Sascha Ott, Vicky Buchanan-Wollaston, Nick Smirnoff, Jim Beynon, Ka...

متن کامل

Epigenetic modification in chromatin machinery and its deregulation in pediatric brain tumors: Insight into epigenetic therapies.

Malignancies are characterized by the reprogramming of epigenetic patterns. This reprogramming includes gains or losses in DNA methylation and disruption of normal patterns of covalent histone modifications, which are associated with changes in chromatin remodeling processes. This review will focus on the mechanisms underlying this reprogramming and, specifically, on the role of histone modific...

متن کامل

Genetic Variation Stimulated by Epigenetic Modification

Homologous recombination is essential for maintaining genomic integrity. A common repair mechanism, it uses a homologous or homeologous donor as a template for repair of a damaged target gene. Such repair must be regulated, both to identify appropriate donors for repair, and to avoid excess or inappropriate recombination. We show that modifications of donor chromatin structure can promote homol...

متن کامل

Transcriptional control: Repression by local chromatin modification

It is becoming increasingly clear that chromatin modification plays a fundamental part in transcriptional control. Recent studies provide new insights into how transcriptional repressors, in addition to blocking activators, may recruit repression complexes that include chromatin modification factors.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Current Opinion in Chemical Biology

سال: 2018

ISSN: 1367-5931

DOI: 10.1016/j.cbpa.2018.01.017